Volume 5 of out Newsletter, "Antiphospho...What?" is available for download!
written by the APS Foundation of America, Inc. Enjoy!!! :)
http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf
We still are looking for articles, book reviews, etc...please email us for more information!
The Faces of APS
Friday, May 25, 2007
Volume 5 of out Newsletter, "Antiphospho...What?" is available for download!
HYDROXYCHLOROQUINE - EVERYTHING OLD IS NEW AGAIN!
HYDROXYCHLOROQUINE - EVERYTHING OLD IS NEW AGAIN!
By: Gale McCarty, MD, FACR, FACP. Hydroxychloroquine (HCQ, or its trade name-Plaquenil) has a long and honored history of use in systemic lupus erythematosus (SLE) as a general medication to decrease activity of the immune system and decrease symptoms. For years it has been approved for use by the FDA for lupus and rheumatoid arthritis, and has been used most frequently for skin and joint manifestations. It is considered a mainstay of therapy for any patient with SLE by many lupus experts and rheumatologists. It has many mechanisms of action, some related to decrease in the activity of the immune system, and some related to effects on blood clotting mechanisms. HCQ belongs to the class of drugs call anti-malarials, which includes Chloroquine and Atabrine. (This does not mean that anyone thinks that SLE or APS is caused by the agent that causes malaria-like most discoveries in medicine, it was the chance observation that patients with some autoimmune diseases who got anti-malarial drugs to prevent malaria when traveling to likely areas of infection noted their symptoms improved on HCQ). One of the most complete and excellent reviews of all the literature on the anti-malarials to which all patients and their physicians are directed is Dr. Dan Wallace’s Chapter 59 in the Wallace-Hahn Dubois’ Lupus Erythematosus textbook. Another excellent review on APS therapy in general has been published by Dr. Robert Roubey.
http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf
INR Monitoring in Patients with Antiphospholipid Antibodies with Finger Stick INR Machines.
INR Monitoring in Patients with Antiphospholipid Antibodies with Finger Stick INR Machines.
by: Stephan Moll, MD. A superb way to monitor INRs (International Normalized Ratio) in patients on oral anticoagulants who do NOT have antiphospholipid antibodies (APLA) is though use of “point of care instruments”, where the INR is tested on blood from a finger stick. This method gives fast results and is used by many physicians’ offices and by some patients at home. However, in patients with APLA on oral anticoagulants these instruments may give inaccurate readings.
http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf
Are Natural Alternatives to Warfarin Safe and Effective?
Are Natural Alternatives to Warfarin Safe and Effective?
Written by: Randy Rauber, Pharm.D Candidate
University of Colorado Health Sciences Center. Reviewed by: Al Lodwick, RPh, MA. Is there any
evidence to support the use of herbal supplement “blood thinners” in patients with antiphospholipid antibody syndrome (APS) as natural alternatives to Warfarin?
http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf
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