Volume 5 of out Newsletter, "Antiphospho...What?" is available for download!

Volume 5 of out Newsletter, "Antiphospho...What?" is available for download!

written by the APS Foundation of America, Inc. Enjoy!!! :)

http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf

We still are looking for articles, book reviews, etc...please email us for more information!

HYDROXYCHLOROQUINE - EVERYTHING OLD IS NEW AGAIN!

HYDROXYCHLOROQUINE - EVERYTHING OLD IS NEW AGAIN!

By: Gale McCarty, MD, FACR, FACP. Hydroxychloroquine (HCQ, or its trade name-Plaquenil) has a long and honored history of use in systemic lupus erythematosus (SLE) as a general medication to decrease activity of the immune system and decrease symptoms. For years it has been approved for use by the FDA for lupus and rheumatoid arthritis, and has been used most frequently for skin and joint manifestations. It is considered a mainstay of therapy for any patient with SLE by many lupus experts and rheumatologists. It has many mechanisms of action, some related to decrease in the activity of the immune system, and some related to effects on blood clotting mechanisms. HCQ belongs to the class of drugs call anti-malarials, which includes Chloroquine and Atabrine. (This does not mean that anyone thinks that SLE or APS is caused by the agent that causes malaria-like most discoveries in medicine, it was the chance observation that patients with some autoimmune diseases who got anti-malarial drugs to prevent malaria when traveling to likely areas of infection noted their symptoms improved on HCQ). One of the most complete and excellent reviews of all the literature on the anti-malarials to which all patients and their physicians are directed is Dr. Dan Wallace’s Chapter 59 in the Wallace-Hahn Dubois’ Lupus Erythematosus textbook. Another excellent review on APS therapy in general has been published by Dr. Robert Roubey.

http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf

INR Monitoring in Patients with Antiphospholipid Antibodies with Finger Stick INR Machines.

INR Monitoring in Patients with Antiphospholipid Antibodies with Finger Stick INR Machines.

by: Stephan Moll, MD. A superb way to monitor INRs (International Normalized Ratio) in patients on oral anticoagulants who do NOT have antiphospholipid antibodies (APLA) is though use of “point of care instruments”, where the INR is tested on blood from a finger stick. This method gives fast results and is used by many physicians’ offices and by some patients at home. However, in patients with APLA on oral anticoagulants these instruments may give inaccurate readings.

http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf

Are Natural Alternatives to Warfarin Safe and Effective?

Are Natural Alternatives to Warfarin Safe and Effective?

Written by: Randy Rauber, Pharm.D Candidate
University of Colorado Health Sciences Center. Reviewed by: Al Lodwick, RPh, MA. Is there any

evidence to support the use of herbal supplement “blood thinners” in patients with antiphospholipid antibody syndrome (APS) as natural alternatives to Warfarin?

http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf

APS in the Community

APS in the Community

written by Seren Estrada. On April 22nd the APSFA made an appearance at the annual March of Dimes WalkAmerica event in Springfield, Virginia.

http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf

MO-KAN Spreads APS Awareness

MO-KAN Spreads APS Awareness

Written by Dana Stuart. “Mo-Kan” is a phrase commonly used in the Missouri-Kansas region to describe various missions or goals that Missouri and Kansas businesses and residents CAN accomplish together. Frequently used for public service announcements, advertisements, and other miscellaneous uses, “Mo-Kan” has become the unofficial slogan for several alliances, which have formed for some very worthy causes. Now “Mo-Kan” spreads APS Awareness!

http://www.apsfa.org/docs/APSFAVol5Spring2007.pdf

June is APS Awareness Month

June is APS Awareness Month

The Proclamation is a call to action for governments around the world to increase their financial support for APS research, awareness and patient services.

Each year, the APS Foundation of America, Inc (APSFA) will revise the Proclamation to reflect the emerging issues that people with APS around the world must face every day. The Proclamation serves to give a single voice to all individuals affected by this devastating and debilitating chronic disease.

Please join the APSFA in urging your government to adopt and make June APS Awareness Month.

WHEREAS, The APS Foundation of America, Inc. has declared June as National Antiphospholipid Antibody Syndrome (APS) Awareness Month and is educating the public and medical community about this clotting disorder and is urging people to "Get in the Flow”; and

WHEREAS, APS is the major cause of young strokes, many miscarriages, both arterial and venous thrombosis, and heart attacks. It has been estimated by some doctors that one third of all of young strokes (defined as under the age of 50) are due to APS. Some doctors believe that 1 in 5 of all Deep Vein Thrombosis (DVTs), Pulmonary Embolisms (PEs), and even worse, amputations are due to APS. And it is believed that 40-50% of patients with Lupus also have APS. Women are more likely than men to be affected by APS. Some estimates say that 75% to 90% of those affected are women. In obstetrics, it is estimated by some doctors that up to 25% of all women with 2 or more spontaneous miscarriages have APS; and

WHEREAS, the APS Foundation of America, Inc is working to bring a national attention to APS as a common factor in multiple miscarriages, thrombosis, young strokes, and heart attacks is vital in order to bring a joint effort to research, funding, early detection, and eventually, prevention and cure for APS; and

WHEREAS, the mission of the APS Foundation of America, Inc. is to offer understanding and support to individuals, family, friends, and care givers of APS; to offer information about and education on APS; to support research regarding APS by keeping the latest information available and referring people to such agencies who do research; to raise funds to provide information and education through public donations, grants, fundraisers, sponsorships, and bequests; and to bring national focus to APS in the United States.

NOW, THEREFORE, BE IT RESOLVED that June is hereby designated as APS AWARENESS MONTH on which the APS Foundation of America, Inc call for increases in public and private sector funding for medical research on APS, targeted education programs for health professionals, patients and the public, and worldwide recognition of APS as a significant public health issue.

Proclaimed This Day, 1 June 2007

Remember Mother's Day!

Vibrant Tulips				Natural Wonders
Clear Day		Stunning Beauty		Pink Kalanchoe		Brighten Your Day
Help support the APS Foundation of America Your generosity has come in the form of donations, volunteering, fundraising efforts, and special event participation -- for that we can never thank you enough. When it comes time for you to show mom that you're thinking of her, we hope you can keep the APS Foundation of America in mind. As part of a new fundraising initiative, when you purchase flowers and gift baskets online from our Flower Petal.com website, you will receive delivery at no additional charge, and 12% of the proceeds are sent to the APS Foundation of America. In fact, you can visit http://apsfa.flowerpetal.com any time of the year to send flowers and gifts for birthdays, graduations, anniversaries and holidays -- with every purchase you make, you will be supporting our efforts. Thank you for your continued support.